FOXO1
Sign in to saveAlso known as FKH1, FKHR, FOXO1A, forkhead box O1
protein-coding gene in the species Homo sapiens
Gene data
FOXO1- Name
- forkhead box O1
- Type
- protein-coding
- Position
- 40,555,667–40,667,612 (−)
- Aliases
- FKH1, FKHR, FOXO1A
- Ensembl
- ENSG00000150907
- RefSeq RNA
- NM_002015.4, XM_011535008.3, XM_011535010.3, XM_047430204.1, XM_054374285.1
- RefSeq protein
- NP_002006.2, XP_011533310.1, XP_011533312.1, XP_047286160.1, XP_054230260.1
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
RNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription repressor activity, RNA polymerase II-specificDNA-binding transcription activator activity, RNA polymerase II-specificDNA-binding transcription activator activity, RNA polymerase II-specificDNA-binding transcription activator activity, RNA polymerase II-specific
Cellular component
Pathways
FoxO signaling pathway - Homo sapiens (human)AMPK signaling pathway - Homo sapiens (human)Longevity regulating pathway - Homo sapiens (human)Longevity regulating pathway - multiple species - Homo sapiens (human)Cellular senescence - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)Thyroid hormone signaling pathway - Homo sapiens (human)Glucagon signaling pathway - Homo sapiens (human)Insulin resistance - Homo sapiens (human)AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
forkhead box O1
- Symbol
- FOXO1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:40,555,667-40,667,612
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein FOXO1 PDB 3CO6.png
Show 8 more facts
- HomoloGene ID
- 1527
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2308
- genomic end
- 40666641
- genomic start
- 40555667
- expressed in
- myometrium
- chromosome
- human chromosome 13
- cytogenetic location
- 13q14.11
via Wikidata · CC0