FSHR
Sign in to saveAlso known as FSHR1, FSHRO, LGR1, ODG1, follicle stimulating hormone receptor
protein-coding gene in the species Homo sapiens
Gene data
FSHR- Name
- follicle stimulating hormone receptor
- Type
- protein-coding
- Position
- 48,962,157–49,154,527 (−)
- Aliases
- FSHR1, FSHRO, LGR1, ODG1
- Ensembl
- ENSG00000170820
- RefSeq RNA
- NM_000145.4, NM_001445714.1, NM_001445715.1, NM_001445716.1, NM_001445717.1
- RefSeq protein
- NP_000136.2, NP_001432643.1, NP_001432644.1, NP_001432645.1, NP_001432646.1
The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].
Gene Ontology
Biological process
MAPK cascadeovarian follicle developmentG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayspermatogenesis
Molecular function
G protein-coupled receptor activityfollicle-stimulating hormone receptor activityfollicle-stimulating hormone receptor activityfollicle-stimulating hormone receptor activityfollicle-stimulating hormone receptor activityprotein bindingG protein-coupled peptide receptor activityprotein-hormone receptor activity
Pathways
cAMP signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Ovarian steroidogenesis - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Hormone ligand-binding receptorsGPCR downstream signallingG alpha (s) signalling eventsGPCR ligand binding
via MyGene.info
Gene · Ensembl
follicle stimulating hormone receptor
- Symbol
- FSHR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:48,962,157-49,154,527
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Follicle-stimulating hormone receptor within Follicle Stimulating Hormone and Receptor complex 1XWD.png
Show 5 more facts
- HomoloGene ID
- 117
- exact match
- identifiers.org/ncbigene/2492
- genomic end
- 49154527
- genomic start
- 49189296
- cytogenetic location
- 2p16.3
via Wikidata · CC0
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adenosine cyclic phosphate
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chorionic gonadotropin
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