FXR1

Also known as FXR1P, FMR1 autosomal homolog 1, MYORIBF, MYOPMIL

Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene.

In the Vinony graph

Vinony's link graph records 15 inbound references to FXR1, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 3.

Vinony links it to 6 Wikipedia language editions.

Gene data

FXR1

Name: FMR1 autosomal homolog 1
Type: protein-coding
Position: 180,868,141–180,982,753 (+)
Aliases: CMYO9A, CMYO9B, CMYP9A, CMYP9B, FXR1P, MYOPMIL, MYORIBF
Ensembl: ENSG00000114416
RefSeq RNA: NM_001013438.3, NM_001013439.3, NM_001363882.1, NM_001441509.1, NM_001441510.1
RefSeq protein: NP_001013456.1, NP_001013457.1, NP_001350811.1, NP_001428438.1, NP_001428439.1

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways

RNA transport - Homo sapiens (human)Disease Diseases of signal transduction by growth factor receptors and second messengers Signaling by BRAF and RAF1 fusions Oncogenic MAPK signaling Bile acids synthesis and enterohepatic circulation

via MyGene.info

Gene · Ensembl

FMR1 autosomal homolog 1

Symbol: FXR1
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:180,868,141-180,982,753
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein FXR1 PDB 2cpq.png

Show 7 more facts

HomoloGene ID: 3573
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/8087
genomic end: 180700541
genomic start: 180585929
chromosome: human chromosome 3
cytogenetic location: 3q26.33

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

Interactions
References
Further reading

Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene.

The protein encoded by this gene is an RNA binding protein that interacts with the functionally similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Excerpted from Wikipedia’s “FXR1” article, available under the CC BY-SA 4.0 licence.