glafenine
Sign in to saveAlso known as Glifanan, Glycerylaminophenaquine, 4-((2-Carboxyphenyl)amino)-7-chloroquinoline alpha-monoglyceride, 2,3-Dihydroxypropyl N-(7-chloro-4-quinolyl) anthranilate, 4-(2'-beta,gamma-Dihydroxypropoxycarbonylphenylamino)-7-chloroquinoline, Glaphenin, Glifan, Glaphenine
Glafenine is a nonsteroidal anti-inflammatory drug (NSAID). Use of glafenine is limited due to the risk of anaphylaxis and acute kidney failure.
Research
207 papers- [Glafenine hepatotoxicity].Medicina clinica · 1988
- Hepatotoxicity of glafenine.Lancet (London, England) · 1978
- [Shock caused by glafenine. Apropos of 7 complications].La Revue de medecine interne · 1989
- The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway.Scientific reports · 2022
- Bioactivation of glafenine by human liver microsomes and peroxidases: identification of electrophilic iminoquinone species and GSH conjugates.Drug metabolism and disposition: the biological fate of chemicals · 2011
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 372.088
Show 3 more facts
- canonical SMILES
- C1=CC=C(C(=C1)C(=O)OCC(CO)O)NC2=C3C=CC(=CC3=NC=C2)Cl
- chemical formula
- C₁₉H₁₇ClN₂O₄
- World Health Organisation international non-proprietary name
- glafenine
Sources (2)
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Encyclopedic overview
2 sectionsContents
- See also
- References
Glafenine is a nonsteroidal anti-inflammatory drug (NSAID). Use of glafenine is limited due to the risk of anaphylaxis and acute kidney failure.
== See also == Floctafenine, a chemically related NSAID
Excerpted from Wikipedia’s “glafenine” article, available under the CC BY-SA 4.0 licence.
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