Structure via PubChem · Public domain (PubChem)
gossypetin
Sign in to saveAlso known as 3,5,7,8,3',4'-hexahydroxyflavone
Gossypetin, also known as '''3,5,7,8,3',4'-hexahydroxyflavone', is a flavonol, a type of flavonoid. It has been isolated from the flowers and the calyx of Hibiscus sabdariffa'' (roselle) and exhibits a strong antibacterial activity. The compound has also been found to act as an antagonist of TrkB. Gossypetin has radioprotective activity.
Chemical data
- Formula
- C15H10O8
- Molecular weight
- 318.23 g/mol
- IUPAC name
- 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxychromen-4-one
- SMILES
- C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O)O
- InChIKey
- YRRAGUMVDQQZIY-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 148 Ų
- H-bond donors
- 6
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- flavone
- Mass
- 318.037567
Show 5 more facts
- found in taxon
- Rhododendron latoucheae
- canonical SMILES
- C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O)O
- chemical formula
- C₁₅H₁₀O₈
- Commons category
- Gossypetin
- has characteristic
- bitterness
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Gossypetin, also known as '''3,5,7,8,3',4'-hexahydroxyflavone', is a flavonol, a type of flavonoid. It has been isolated from the flowers and the calyx of Hibiscus sabdariffa (roselle) and exhibits a strong antibacterial activity. The compound has also been found to act as an antagonist of TrkB. Gossypetin has radioprotective activity.
The enzyme 8-hydroxyquercetin 8-O-methyltransferase uses S-adenosyl methionine and gossypetin to produce S''-adenosylhomocysteine and 3,5,7,3',4'-pentahydroxy-8-methoxyflavone.
Excerpted from Wikipedia’s “gossypetin” article, available under the CC BY-SA 4.0 licence.