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GeneQ18052956· pop 6· linked from 2 articles

GPHA2

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Also known as A2, GPA2, ZSIG51, glycoprotein hormone alpha 2, glycoprotein hormone subunit alpha 2

Glycoprotein hormone alpha-2 is a protein that in humans is encoded by the GPHA2 gene.

Gene data

GPHA2

Name: glycoprotein hormone subunit alpha 2
Type: protein-coding
Position: 64,934,471–64,935,893 (−)
Aliases: A2, GPA2, ZSIG51
Ensembl: ENSG00000149735
RefSeq RNA: NM_130769.4, XM_011544776.3, XM_047426491.1, XM_054367885.1, XM_054367886.1
RefSeq protein: NP_570125.1, XP_011543078.1, XP_047282447.1, XP_054223860.1, XP_054223861.1

GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008].

Gene Ontology

Biological process

cell surface receptor signaling pathway cell surface receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway

Molecular function

hormone activity protein binding thyrotropin-releasing hormone receptor binding thyrotropin-releasing hormone receptor binding protein heterodimerization activity

Cellular component

extracellular region extracellular region extracellular region extracellular region

Pathways

Signal Transduction Signaling by GPCR Class A/1 (Rhodopsin-like receptors)Hormone ligand-binding receptors GPCR downstream signalling G alpha (s) signalling events GPCR ligand binding

via MyGene.info

Gene · Ensembl

glycoprotein hormone subunit alpha 2

Symbol: GPHA2
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:64,934,471-64,935,894
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 15605
exact match: identifiers.org/ncbigene/170589
genomic start: 64701943
genomic end: 64935893
cytogenetic location: 11q13.1

Sources (3)

via Wikidata · CC0

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Article

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Contents

References
Further reading

Glycoprotein hormone alpha-2 is a protein that in humans is encoded by the GPHA2 gene.

GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002). (Supplied by OMIM.)

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via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 11