HCRTR2
Sign in to saveAlso known as OX2R, Hypocretin (orexin) receptor 2, hypocretin receptor 2, ORXR2, OXR2
protein-coding gene in the species Homo sapiens
Gene data
HCRTR2- Name
- hypocretin receptor 2
- Type
- protein-coding
- Position
- 55,106,460–55,282,617 (+)
- Aliases
- ORXR2, OX2R, OXR2
- Ensembl
- ENSG00000137252
- RefSeq RNA
- NM_001384272.1, NM_001526.5, XM_017010798.2, XM_054355266.1
- RefSeq protein
- NP_001371201.1, NP_001517.2, XP_016866287.1, XP_054211241.1
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009].
Gene Ontology
Biological process
Molecular function
Pathways
Neuroactive ligand-receptor interaction - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Peptide ligand-binding receptorsGPCR downstream signallingOrexin and neuropeptides FF and QRFP bind to their respective receptorsG alpha (q) signalling eventsGPCR ligand bindingPeptide GPCRs
via MyGene.info
Gene · Ensembl
hypocretin receptor 2
- Symbol
- HCRTR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:55,106,460-55,282,617
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI