HFM1
Sign in to saveAlso known as MER3, POF9, SEC63D1, Si-11, Si-11-6, helicase, HFM1, ATP-dependent DNA helicase homolog, HFM1, ATP dependent DNA helicase homolog
HFM1 is a gene that in humans encodes a protein necessary for homologous recombination of chromosomes. Biallelic mutations in HFM1 cause recessive primary ovarian insufficiency.
Gene data
HFM1- Name
- helicase for meiosis 1
- Type
- protein-coding
- Position
- 91,260,761–91,404,856 (−)
- Aliases
- MER3, POF9, SEC63D1, Si-11, Si-11-6, helicase
- Ensembl
- ENSG00000162669
- RefSeq RNA
- NM_001017975.6, NR_165455.1, XM_011540849.2, XM_011540850.3, XM_011540851.2
- RefSeq protein
- NP_001017975.5, XP_011539151.1, XP_011539152.1, XP_011539153.1, XP_011539154.1
The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
helicase for meiosis 1
- Symbol
- HFM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:91,260,761-91,404,856
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 87103
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/164045
- chromosome
- human chromosome 1
- genomic start
- 91726323
- genomic end
- 91404856
- cytogenetic location
- 1p22.2
- expressed in
- ganglionic eminence
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
HFM1 is a gene that in humans encodes a protein necessary for homologous recombination of chromosomes. Biallelic mutations in HFM1 cause recessive primary ovarian insufficiency.
== References ==
Excerpted from Wikipedia’s “HFM1” article, available under the CC BY-SA 4.0 licence.