Structure via PubChem · Public domain (PubChem)
Hypericin
Sign in to saveAlso known as 1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione, hypericum red
chemische verbinding
In the Vinony graph
Vinony's link graph records 205 inbound references to Hypericin, and connects out to DL-glutamic acid, NMDA receptor and pentamidine.
Vinony files it under 3-Hydroxypropenals within hydroxyquinones, Biological pigments and Chembox image size set.
Vinony links it to 22 Wikipedia language editions.
Chemical data
- Formula
- C30H16O8
- Molecular weight
- 504.4 g/mol
- IUPAC name
- 5,7,11,18,22,24-hexahydroxy-13,16-dimethyloctacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(27),2(28),3,5,7,10,12,14,16,18,21,23,25-tridecaene-9,20-dione
- SMILES
- CC1=CC(=C2C3=C4C5=C(C(=CC(=C5C2=O)O)O)C6=C7C4=C8C(=C13)C(=CC(=C8C(=O)C7=C(C=C6O)O)O)C)O
- InChIKey
- BTXNYTINYBABQR-UHFFFAOYSA-N
- XLogP
- 6.9
- Polar surface area
- 156 Ų
- H-bond donors
- 6
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- HIV infection, Cutaneous T-cell lymphoma, mycosis fungoides, psoriasis vulgaris
via ChEMBL · EBI
Research
1,653 papers- Hypericin: A natural anthraquinone as promising therapeutic agent.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2023
- Hypericin in photobiological assays: An overview.Photodiagnosis and photodynamic therapy · 2021
- Hypericin-mediated photodynamic therapy for the treatment of cancer: a review.The Journal of pharmacy and pharmacology · 2021
- Hypericin as a promising natural bioactive naphthodianthrone: A review of its pharmacology, pharmacokinetics, toxicity, and safety.Phytotherapy research : PTR · 2023
- Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2022
via PubMed
Wikidata facts
- Mass
- 504.084517
Show 5 more facts
- found in taxon
- Hypericum aucheri
- chemical formula
- C₃₀H₁₆O₈
- subject has role
- enzyme inhibitor
- canonical SMILES
- CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O
- Commons category
- Hypericin
via Wikidata · CC0
Connections
DL-glutamic acid
Entity
NMDA receptor
Entity
pentamidine
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1-aminocyclopropanecarboxylic acid
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racemorphan
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DL-methorphan
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lanicemine
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selfotel
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rapastinel
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PCPr
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hydrogen
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skin
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zinc
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magnesium
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xenon
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cocaine
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digital object identifier
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International Standard Serial Number
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chemical formula
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benzene
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