procyclidine
Also known as 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol, 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol, 1-cyclohexyl-1-phenyl-3-(1-pyrrolidinyl)-1-propanol, 1-cyclohexyl-1-phenyl-3-pyrrolidino-propan-1-ol, 1-cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol
Procyclidine is an anticholinergic drug principally used for the treatment of drug-induced parkinsonism, akathisia and acute dystonia, Parkinson's disease, and idiopathic or secondary dystonia.
Research
289 papers- Procyclidine abuse.The British journal of psychiatry : the journal of mental science · 1986
- Dystonia.BMJ clinical evidence · 2014
- Teenage procyclidine abuse.Lancet (London, England) · 1985
- In vivo Evaluation of Antioxidant Activity of Chamomile Extract against Procyclidine-Induced Oxidative Stress: Potential Application in Cancer Prevention.Asian Pacific journal of cancer prevention : APJCP · 2024
- Effects of procyclidine on eye movements in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2003
via PubMed
Article
10 sectionsContents
- Medical uses
- Side effects
- Overdose
- Pharmacology
- Pharmacodynamics
- Chemistry
- Synthesis
- See also
- References
- Further reading
Procyclidine is an anticholinergic drug principally used for the treatment of drug-induced parkinsonism, akathisia and acute dystonia, Parkinson's disease, and idiopathic or secondary dystonia.
== Medical uses == It is used in patients with parkinsonism and akathisia, and to reduce the side effects of antipsychotic treatment given for schizophrenia. Procyclidine is also a second-line drug for the treatment of Parkinson's disease. It improves tremor but not rigidity or bradykinesia.