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GeneQ18027842· pop 5· linked from 142 articles

Also known as CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor

protein-coding gene in the species Homo sapiens

Gene data

IL7R
Name
interleukin 7 receptor
Type
protein-coding
Aliases
CD127, CDW127, IL-7R-alpha, IL-7Ralpha, IL7RA, IL7Ralpha, ILRA, IMD104, lnc-IL7R, sIL-7R

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015].

via MyGene.info

Gene · Ensembl

interleukin 7 receptor

Symbol
IL7R
Biotype
Protein coding
Organism
Homo sapiens
Location
5:35,852,695-35,879,603
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
IL-7receptor and signaling.jpg
Show 5 more facts
HomoloGene ID
1646
genomic end
35879705
genomic start
35852797
cytogenetic location
5p13.2
Sources (6)

via Wikidata · CC0

Available in 5 languages

via Wikidata sitelinks · CC0

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