IL7R
Sign in to saveAlso known as CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor
protein-coding gene in the species Homo sapiens
Gene data
IL7R- Name
- interleukin 7 receptor
- Type
- protein-coding
- Position
- 35,852,695–35,879,603 (+)
- Aliases
- CD127, CDW127, IL-7R-alpha, IL-7Ralpha, IL7RA, IL7Ralpha, ILRA, IMD104, lnc-IL7R, sIL-7R
- Ensembl
- ENSG00000168685
- RefSeq RNA
- NM_001410734.1, NM_001437963.1, NM_001437964.1, NM_002185.5, NR_120485.3
- RefSeq protein
- NP_001397663.1, NP_001424892.1, NP_001424893.1, NP_002176.2, XP_047273105.1
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
interleukin 7 receptor
- Symbol
- IL7R
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:35,852,695-35,879,603
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI