KCNC4

Also known as C1orf30, HKSHIIIC, KSHIIIC, KV3.4, potassium voltage-gated channel subfamily C member 4

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.

In the Vinony graph

Within Vinony's link graph, KCNC4 is referenced by 305 other articles, and connects out to PubMed, Ensembl genome database project and water.

Vinony files it under Genes on human chromosome 1 and Ion channels.

Its subject is documented across 5 Wikipedia language editions.

Gene data

KCNC4

Name: potassium voltage-gated channel subfamily C member 4
Type: protein-coding
Position: 110,210,095–110,283,100 (+)
Aliases: C1orf30, HKSHIIIC, KSHIIIC, KV3.4
Ensembl: ENSG00000116396
RefSeq RNA: NM_001039574.3, NM_001377330.1, NM_001377331.1, NM_004978.6, NM_153763.2
RefSeq protein: NP_001034663.1, NP_001364259.1, NP_001364260.1, NP_004969.2, XP_006710688.1

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].

Pathways

Neuronal System Potassium Channels Voltage gated Potassium channels

via MyGene.info

Gene · Ensembl

potassium voltage-gated channel subfamily C member 4

Symbol: KCNC4
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:110,210,095-110,283,100
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein KCNC4 PDB 1b4g.png

Show 8 more facts

HomoloGene ID: 68427
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/3749
genomic start: 110210314
chromosome: human chromosome 1
genomic end: 110825722
cytogenetic location: 1p13.3
expressed in: gonad

Sources (4)

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Encyclopedic overview

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Contents

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Further reading

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.

Excerpted from Wikipedia’s “KCNC4” article, available under the CC BY-SA 4.0 licence.