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GeneQ18028147· pop 5· linked from 305 articles

Also known as C1orf30, HKSHIIIC, KSHIIIC, KV3.4, potassium voltage-gated channel subfamily C member 4

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.

Gene data

KCNC4
Name
potassium voltage-gated channel subfamily C member 4
Type
protein-coding
Aliases
C1orf30, HKSHIIIC, KSHIIIC, KV3.4

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].

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Gene · Ensembl

potassium voltage-gated channel subfamily C member 4

Symbol
KCNC4
Biotype
Protein coding
Organism
Homo sapiens
Location
1:110,210,095-110,283,100
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein KCNC4 PDB 1b4g.png
Show 5 more facts
HomoloGene ID
68427
genomic start
110210314
genomic end
110825722
cytogenetic location
1p13.3
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Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.

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