KCNIP1

Also known as KCHIP1, VABP, potassium voltage-gated channel interacting protein 1

Kv channel-interacting protein 1 also known as KChIP1 is a protein that in humans is encoded by the KCNIP1 gene.

Gene data

KCNIP1

Name: potassium voltage-gated channel interacting protein 1
Type: protein-coding
Position: 170,353,487–170,736,632 (+)
Aliases: KCHIP1, VABP
Ensembl: ENSG00000182132
RefSeq RNA: NM_001034837.3, NM_001034838.3, NM_001278339.2, NM_001278340.2, NM_014592.4
RefSeq protein: NP_001030009.1, NP_001030010.1, NP_001265268.1, NP_001265269.1, NP_055407.1

This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013].