KLK11

Also known as PRSS20, TLSP, kallikrein related peptidase 11

Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.

Gene data

KLK11

Name: kallikrein related peptidase 11
Type: protein-coding
Position: 51,022,216–51,028,039 (−)
Aliases: IEKD, PRSS20, TLSP
Ensembl: ENSG00000167757
RefSeq RNA: NM_001136032.3, NM_001167605.2, NM_006853.3, NM_144947.3, XM_005258439.4
RefSeq protein: NP_001129504.1, NP_001161077.1, NP_006844.1, NP_659196.1, XP_005258496.1

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016].

Gene Ontology

Biological process

proteolysis

~1 min read

Article

3 sections

Contents

References
Further reading
External links

Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in two transcript variants encoding two different isoforms which are differentially expressed.