KLK11
Sign in to saveAlso known as PRSS20, TLSP, kallikrein related peptidase 11
Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.
In the Vinony graph
Within Vinony's link graph, KLK11 is referenced by 138 other articles, and connects out to Q180686, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 5 Wikipedia language editions.
Gene data
KLK11- Name
- kallikrein related peptidase 11
- Type
- protein-coding
- Position
- 51,022,216–51,028,060 (−)
- Aliases
- IEKD, PRSS20, TLSP
- Ensembl
- ENSG00000167757
- RefSeq RNA
- NM_001136032.3, NM_001167605.2, NM_006853.3, NM_144947.3, XM_005258439.4
- RefSeq protein
- NP_001129504.1, NP_001161077.1, NP_006844.1, NP_659196.1, XP_005258496.1
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
kallikrein related peptidase 11
- Symbol
- KLK11
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:51,022,216-51,028,060
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 27048
- exact match
- identifiers.org/ncbigene/11012
- genomic end
- 51531295
- genomic start
- 51525472
- cytogenetic location
- 19q13.41
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in two transcript variants encoding two different isoforms which are differentially expressed.
Excerpted from Wikipedia’s “KLK11” article, available under the CC BY-SA 4.0 licence.