KMT2E
Sign in to saveAlso known as HDCMC04P, MLL5, NKp44L, lysine methyltransferase 2E, ODLURO, lysine methyltransferase 2E (inactive), SETD5B
'Histone-lysine N-methyltransferase 2E, also known as myeloid/lymphoid or mixed-lineage leukemia 5 (MLL5'), is a protein that in humans is encoded by the gene.
In the Vinony graph
Within Vinony's link graph, KMT2E is referenced by 5 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Its subject is documented across 5 Wikipedia language editions.
Gene data
KMT2E- Name
- lysine methyltransferase 2E (inactive)
- Type
- protein-coding
- Position
- 104,940,943–105,116,242 (+)
- Aliases
- HDCMC04P, MLL5, NKp44L, ODLURO, SETD5B
- Ensembl
- ENSG00000005483
- RefSeq RNA
- NM_001410908.1, NM_001445725.1, NM_001445726.1, NM_001445727.1, NM_001445728.1
- RefSeq protein
- NP_001397837.1, NP_001432654.1, NP_001432655.1, NP_001432656.1, NP_001432657.1
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
lysine methyltransferase 2E (inactive)
- Symbol
- KMT2E
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:104,940,943-105,116,242
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 18822
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55904
- genomic end
- 105115019
- genomic start
- 104940943
- chromosome
- human chromosome 7
- cytogenetic location
- 7q22.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical importance
- References
- Further reading
'Histone-lysine N-methyltransferase 2E, also known as myeloid/lymphoid or mixed-lineage leukemia 5 (MLL5'), is a protein that in humans is encoded by the gene.
==Function==
Excerpted from Wikipedia’s “KMT2E” article, available under the CC BY-SA 4.0 licence.