LANCL2
Sign in to saveAlso known as GPR69B, TASP, LanC like 2
LanC-like protein 2 is a protein that in humans is encoded by the LANCL2 gene. It is a protein broadly expressed in the plasma a nuclear membranes of immune, epithelial and muscle cells and a potential therapeutic target for chronic inflammatory, metabolic and immune-mediated diseases such as Crohn's disease and diabetes.
In the Vinony graph
Within Vinony's link graph, LANCL2 is referenced by 3 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Its subject is documented across 5 Wikipedia language editions.
Gene data
LANCL2- Name
- LanC like glutathione S-transferase 2
- Type
- protein-coding
- Position
- 55,365,282–55,433,741 (+)
- Aliases
- GPR69B, TASP
- Ensembl
- ENSG00000132434
- RefSeq RNA
- NM_018697.4, XM_047420614.1
- RefSeq protein
- NP_061167.1, XP_047276570.1
Enables phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of abscisic acid-activated signaling pathway. Located in several cellular components, including cortical actin cytoskeleton; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
LanC like glutathione S-transferase 2
- Symbol
- LANCL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:55,365,282-55,433,741
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 23116
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55915
- chromosome
- human chromosome 7
- genomic start
- 55365337
- genomic end
- 55433737
- cytogenetic location
- 7p11.2
Sources (4)
via Wikidata · CC0
~3 min read
Encyclopedic overview
4 sectionsContents
- Function
- Activators
- References
- Further reading
LanC-like protein 2 is a protein that in humans is encoded by the LANCL2 gene. It is a protein broadly expressed in the plasma a nuclear membranes of immune, epithelial and muscle cells and a potential therapeutic target for chronic inflammatory, metabolic and immune-mediated diseases such as Crohn's disease and diabetes.
== Function ==
Excerpted from Wikipedia’s “LANCL2” article, available under the CC BY-SA 4.0 licence.