Structure via PubChem · Public domain (PubChem)
levosulpiride
Sign in to saveAlso known as S-(-)-sulpiride, (S)-(-)-5-aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, (S)-sulpiride, (-)-sulpiride, (S)-(-)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide, S-(-)-N-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide, (-)-N-{[(S)-1-ethyl-2-pyrrolidinyl]methyl}-5-sulfamoyl-o-anisamide
Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis. It is taken by mouth.
Key facts
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 443990153
- Drug.image
- Levosulpiride.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Dislep, Sulpepta, others
- Drug.routes_of_administration
- Oral
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- AL07
- Drug.CAS_number
- 23672-07-3
- Drug.PubChem
- 688272
- Drug.IUPHAR_ligand
- 958
- Drug.DrugBank
- DB16021
- Drug.ChemSpiderID
- 599749
- Drug.UNII
- JTG7R315LK
- Drug.KEGG
- D07312
- Drug.ChEBI
- 64119
- Drug.ChEMBL
- 267044
via Wikipedia infobox
Chemical data
- Formula
- C15H23N3O4S
- Molecular weight
- 341.4 g/mol
- IUPAC name
- N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- dyspepsia, psychosis, Agitation
via ChEMBL · EBI
Wikidata facts
- Mass
- 341.140927
Show 5 more facts
- chemical formula
- C₁₅H₂₃N₃O₄S
- isomeric SMILES
- CCN1CCC[C@H]1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC
- canonical SMILES
- CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC
- World Health Organisation international non-proprietary name
- levosulpiride
- Commons category
- Levosulpiride
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Chemistry
- References
Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis. It is taken by mouth.
It is a selective antagonist of the dopamine D2 receptor and an agonist of the serotonin 5-HT4 receptor. Chemically, it is a benzamide and the (S)-(−)-enantiomer of sulpiride.