levosulpiride
Also known as S-(-)-sulpiride, (S)-(-)-5-aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, (S)-sulpiride, (-)-sulpiride, (S)-(-)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide, S-(-)-N-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide, (-)-N-{[(S)-1-ethyl-2-pyrrolidinyl]methyl}-5-sulfamoyl-o-anisamide
Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis. It is taken by mouth.
Key facts
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 443990153
- Drug.image
- Levosulpiride.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Dislep, Sulpepta, others
- Drug.routes_of_administration
- Oral
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- AL07
- Drug.CAS_number
- 23672-07-3
- Drug.PubChem
- 688272
- Drug.IUPHAR_ligand
- 958
- Drug.DrugBank
Article
6 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Chemistry
- References
Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis. It is taken by mouth.
It is a selective antagonist of the dopamine D2 receptor and an agonist of the serotonin 5-HT4 receptor. Chemically, it is a benzamide and the (S)-(−)-enantiomer of sulpiride.