LIMA1

Also known as EPLIN, SREBP3, LIM domain and actin binding 1, LDLCQ8

LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene.

In the Vinony graph

Vinony's link graph records 2 inbound references to LIMA1, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 12.

Vinony links it to 6 Wikipedia language editions.

Gene data

LIMA1

Name: LIM domain and actin binding 1
Type: protein-coding
Position: 50,175,788–50,283,550 (−)
Aliases: EPLIN, LDLCQ8, SREBP3
Ensembl: ENSG00000050405
RefSeq RNA: NM_001113546.2, NM_001113547.2, NM_001243775.2, NM_001394886.1, NM_001394887.1
RefSeq protein: NP_001107018.1, NP_001107019.1, NP_001230704.1, NP_001381815.1, NP_001381816.1

This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011].

via MyGene.info

Gene · Ensembl

LIM domain and actin binding 1

Symbol: LIMA1
Biotype: Protein coding
Organism: Homo sapiens
Location: 12:50,175,788-50,283,550
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein LIMA1 PDB 2d8y.png

Show 8 more facts

HomoloGene ID: 9484
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/51474
genomic end: 50677329
genomic start: 50569571
chromosome: human chromosome 12
cytogenetic location: 12q13.12
expressed in: gastric mucosa

Sources (3)

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Encyclopedic overview

2 sections

Contents

References
Further reading

LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene.

EPLIN is a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles (Maul et al., 2003).[supplied by OMIM]

Excerpted from Wikipedia’s “LIMA1” article, available under the CC BY-SA 4.0 licence.