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linopristin
Sign in to saveLinopristin is an antibiotic of the streptogramin B class. It has been described as a pristinamycin IA derivative, though it is actually more similar to quinupristin. NCATS Inxight describes it as a chemically modified version of quinupristin.
In the Vinony graph
Within Vinony's link graph, linopristin is referenced by 111 other articles, and connects out to antibiotic, digital object identifier and chemical formula.
Vinony files it under Antibiotics, Chembox image size set and Depsipeptides.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C50H63N9O10
- Molecular weight
- 950.1 g/mol
- IUPAC name
- N-[(3S,6S,12R,15S,16R,19S,22S)-3-[[4-(dimethylamino)phenyl]methyl]-12-ethyl-4,16-dimethyl-25-(morpholin-4-ylmethyl)-2,5,11,14,18,21-hexaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentazatricyclo[20.4.0.06,10]hexacos-24-en-15-yl]-3-hydroxypyridine-2-carboxamide
- SMILES
- CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3CC(=CC[C@H]3C(=O)N[C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CN6CCOCC6)CC7=CC=C(C=C7)N(C)C)C
- InChIKey
- NVGNYGXBILPHOS-VXNAYKIUSA-N
- XLogP
- 3.1
- Polar surface area
- 223 Ų
- H-bond donors
- 4
- H-bond acceptors
- 13
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 949.47
Show 3 more facts
- chemical formula
- C₅₀H₆₃N₉O₁₀
- canonical SMILES
- CCC1C(=O)N2CCCC2C(=O)N(C(C(=O)N3CC(=CCC3C(=O)NC(C(=O)OC(C(C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CN6CCOCC6)CC7=CC=C(C=C7)N(C)C)C
- isomeric SMILES
- CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3CC(=CC[C@H]3C(=O)N[C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CN6CCOCC6)CC7=CC=C(C=C7)N(C)C)C
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Chembox | ImageFile = Linopristin.svg | ImageClass = skin-invert-image | ImageSize = 200px | ImageAlt = | SystematicName = N-[(6R,9S,10R,13S,15aS,22S,24aS)-22-{[4-(Dimethylamino)phenyl]methyl}-6-ethyl-10,23-dimethyl-18-[(morpholin-4-yl)methyl]-5,8,12,15,21,24-hexaoxo-13-phenyl-1,2,3,5,6,7,8,9,10,13,14,15,15a,16,19,21,22,23,24,24a-icosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl]-3-hydroxypyridine-2-carboxamide | OtherNames = RPR 202698; RPR 202868 |Section1= |Section2= |Section3= }}
Linopristin is an antibiotic of the streptogramin B class. It has been described as a pristinamycin IA derivative, though it is actually more similar to quinupristin. NCATS Inxight describes it as a chemically modified version of quinupristin.
Excerpted from Wikipedia’s “linopristin” article, available under the CC BY-SA 4.0 licence.