LTBR
Sign in to saveAlso known as CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3
protein-coding gene in the species Homo sapiens
Gene data
LTBR- Name
- lymphotoxin beta receptor
- Type
- protein-coding
- Position
- 6,375,045–6,391,571 (+)
- Aliases
- D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3
- Ensembl
- ENSG00000111321
- RefSeq RNA
- NM_001270987.2, NM_001414303.1, NM_001414304.1, NM_001414305.1, NM_001414306.1
- RefSeq protein
- NP_001257916.1, NP_001401232.1, NP_001401233.1, NP_001401234.1, NP_001401235.1
This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
lymphotoxin beta receptor
- Symbol
- LTBR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:6,375,045-6,391,571
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Lymphotoxin b receptor.png
Show 5 more facts
- HomoloGene ID
- 1753
- exact match
- identifiers.org/ncbigene/4055
- genomic end
- 6500733
- genomic start
- 6484211
- cytogenetic location
- 12p13.31
via Wikidata · CC0