MAN1A1

Also known as HUMM3, HUMM9, MAN9, mannosidase alpha class 1A member 1

Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA is an enzyme that in humans is encoded by the MAN1A1 gene.

In the Vinony graph

Vinony's link graph records 2 inbound references to MAN1A1, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 6.

Vinony links it to 5 Wikipedia language editions.

Gene data

MAN1A1

Name: mannosidase alpha class 1A member 1
Type: protein-coding
Position: 119,177,116–119,349,798 (−)
Aliases: HUMM3, HUMM9, MAN9
Ensembl: ENSG00000111885
RefSeq RNA: NM_005907.4, XM_005266986.5, XM_011535833.3, XM_047418775.1, XM_054355440.1
RefSeq protein: NP_005898.2, XP_005267043.1, XP_011534135.1, XP_047274731.1, XP_054211415.1

This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. [provided by RefSeq, Jul 2012].

Pathways

N-Glycan biosynthesis - Homo sapiens (human)Various types of N-glycan biosynthesis - Homo sapiens (human)Protein processing in endoplasmic reticulum - Homo sapiens (human)Membrane Trafficking Metabolism of proteins Asparagine N-linked glycosylation Vesicle-mediated transport Post-translational protein modification Intra-Golgi traffic Intra-Golgi and retrograde Golgi-to-ER traffic

via MyGene.info

Gene · Ensembl

mannosidase alpha class 1A member 1

Symbol: MAN1A1
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:119,177,116-119,349,798
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein MAN1A1 PDB 1nxc.png

Show 7 more facts

exact match: identifiers.org/ncbigene/4121
cytogenetic location: 6q22.31
HomoloGene ID: 4316
found in taxon: Homo sapiens
genomic end: 119670926
genomic start: 119177205
chromosome: human chromosome 6

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA is an enzyme that in humans is encoded by the MAN1A1 gene.

This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the removal of 3 distinct mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases.

Excerpted from Wikipedia’s “MAN1A1” article, available under the CC BY-SA 4.0 licence.