KAT2A
Sign in to saveAlso known as GCN5, GCN5L2, PCAF-b, hGCN5, lysine acetyltransferase 2A
__NOTOC__ Histone acetyltransferase KAT2A is an enzyme that in humans is encoded by the KAT2A gene.
In the Vinony graph
Within Vinony's link graph, KAT2A is referenced by 18 other articles, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Its subject is documented across 5 Wikipedia language editions.
Gene data
KAT2A- Name
- lysine acetyltransferase 2A
- Type
- protein-coding
- Position
- 42,113,109–42,121,382 (−)
- Aliases
- GCN5, GCN5L2, PCAF-b, hGCN5
- Ensembl
- ENSG00000108773
- RefSeq RNA
- NM_001376227.1, NM_021078.3, XM_006721818.5, XM_054315713.1
- RefSeq protein
- NP_001363156.1, NP_066564.2, XP_006721881.1, XP_054171688.1
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
lysine acetyltransferase 2A
- Symbol
- KAT2A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:42,113,109-42,121,382
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GCN5L2 PDB 1f68.png
Show 8 more facts
- HomoloGene ID
- 41343
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2648
- chromosome
- human chromosome 17
- genomic start
- 42113111
- genomic end
- 42121367
- cytogenetic location
- 17q21.2
- expressed in
- canal of the cervix
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
__NOTOC__ Histone acetyltransferase KAT2A is an enzyme that in humans is encoded by the KAT2A gene.
== Interactions ==
Excerpted from Wikipedia’s “KAT2A” article, available under the CC BY-SA 4.0 licence.