بتا-مانوزیداز
Sign in to saveAlso known as MANB1, mannosidase beta
β-Mannosidase (}, mannanase, mannase, β-D-mannosidase, β-mannoside mannohydrolase, exo-β-D-mannanase, lysosomal β A mannosidase) is an enzyme with systematic name β-D-mannoside mannohydrolase, which is in humans encoded by the MANBA gene. This enzyme catalyses the following chemical reaction
In the Vinony graph
Within Vinony's link graph, بتا-مانوزیداز is referenced by 34 other articles, and connects out to PubMed, PubMed Central and human chromosome 4.
It is catalogued under topics including EC 3.2.1 and Genes on human chromosome 4.
Its subject is documented across 10 Wikipedia language editions.
Key facts
- Enzyme.Name
- β-Mannosidase
- Enzyme.EC_number
- 3.2.1.25
- Enzyme.CAS_number
- 9025-43-8
- Enzyme.GO_code
- 0004567
via Wikipedia infobox
Gene data
MANBA- Name
- mannosidase beta
- Type
- protein-coding
- Position
- 102,630,770–102,761,000 (−)
- Aliases
- MANB1
- Ensembl
- ENSG00000109323
- RefSeq RNA
- NM_005908.4, XM_047415692.1, XM_047415693.1, XM_047415694.1, XM_054350029.1
- RefSeq protein
- NP_005899.3, XP_047271648.1, XP_047271649.1, XP_047271650.1, XP_054206004.1
This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
mannosidase beta
- Symbol
- MANBA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:102,630,770-102,761,000
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 4317
- exact match
- identifiers.org/ncbigene/4126
- chromosome
- human chromosome 4
- genomic end
- 103682151
- cytogenetic location
- 4q24
- genomic start
- 102630770
- genetic association
- beta-mannosidosis
- Commons category
- Beta-mannosidase
via Wikidata · CC0