MAPK3
Sign in to saveAlso known as ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3
Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1, is an enzyme that in humans is encoded by the MAPK3 gene.
Gene data
MAPK3- Name
- mitogen-activated protein kinase 3
- Type
- protein-coding
- Aliases
- ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
mitogen-activated protein kinase 3
- Symbol
- MAPK3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:30,114,104-30,123,506
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 55682
- exact match
- identifiers.org/ncbigene/5595
- genomic end
- 30134827
- genomic start
- 30125426
- cytogenetic location
- 16p11.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
7 sectionsContents
- Function
- Clinical significance
- Signaling pathways
- Interactions
- References
- Further reading
- External links
Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1, is an enzyme that in humans is encoded by the MAPK3 gene.
== Function ==