Structure via PubChem · Public domain (PubChem)
midecamycin acetate
Sign in to saveMiocamycin is a macrolide antibiotic. It has a spectrum activity similar to that of Erythromycin, but shows higher antimicrobial effect against certain bacteria including Legionella pneumophila (the causative agent of Legionnaires' Disease), Mycoplasma hominis, and Ureaplasma urealyticum. In-vivo studies have further expounded on Miocamycin's efficacy, reporting that the medication is more effective than in-vitro data suggests.
Chemical data
- Formula
- C45H71NO17
- Molecular weight
- 898 g/mol
- IUPAC name
- [(4R,5S,7R,9R,10R,11E,13E,16R)-10-acetyloxy-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4-acetyloxy-4,6-dimethyl-5-propanoyloxyoxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
- Indications
- bacterial disease
via ChEMBL · EBI
Research
242 papers- [Diagnosis and treatment of acute tonsillopharyngitis. Consensus document update].Anales de pediatria · 2020
- Macrolides allergy.Current pharmaceutical design · 2008
- Bacteriological evaluation of midecamycin acetate and its metabolites.The Japanese journal of antibiotics · 1982
- Midecamycin Is Inactivated by Several Different Sugar Moieties at Its Inactivation Site.International journal of molecular sciences · 2021
- Effect of midecamycin acetate on gastrointestinal motility in humans.International journal of clinical pharmacology research · 1992
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 897.472
Show 4 more facts
- chemical formula
- C₄₅H₇₁NO₁₇
- isomeric SMILES
- CCC(=O)O[C@@H]1CC(=O)O[C@@H](C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]1OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)OC(=O)CC)(C)OC(=O)C)N(C)C)O)CC=O)C)OC(=O)C)C
- canonical SMILES
- CCC(=O)OC1CC(=O)OC(CC=CC=CC(C(CC(C(C1OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)OC(=O)CC)(C)OC(=O)C)N(C)C)O)CC=O)C)OC(=O)C)C
- subject has role
- antibiotic
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | verifiedrevid = 444015174 | IUPAC_name = (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4S,5R,6S,7R,9R,10R,11E,13E,16R)-10-(acetyloxy)-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-propoxy-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-3-propoxyoxan-4-yl acetate | image = Miocamycin.png | image_class = skin-invert-image
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “midecamycin acetate” article, available under the CC BY-SA 4.0 licence.