MRPL4

Name

mitochondrial ribosomal protein L4

Type

protein-coding

Position

10,251,901–10,260,060 (+)

Aliases

CGI-28, L4mt, uL4m

Ensembl

ENSG00000105364

RefSeq RNA

NM_001411149.1, NM_015956.3, NM_146387.2, NM_146388.2

RefSeq protein

NP_001398078.1, NP_057040.2, NP_666499.1, NP_666500.1

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitochondrial ribosomal protein L4

Symbol

MRPL4

Biotype

Protein coding

Organism

Homo sapiens

Location

19:10,251,901-10,260,060

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

PBB Protein MRPL11 image.jpg

via Wikidata · CC0