NMT1
Sign in to saveAlso known as AW536594, NMT, N-myristoyltransferase 1
protein-coding gene in the species Homo sapiens
In the Vinony graph
Vinony's link graph records 10 inbound references to NMT1, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
Vinony files it under EC 2.3.1, Genes on human chromosome 17 and Human proteins.
Vinony links it to 6 Wikipedia language editions.
Gene data
NMT1- Name
- N-myristoyltransferase 1
- Type
- protein-coding
- Position
- 44,957,992–45,109,016 (+)
- Aliases
- HsNMT1, NMT
- Ensembl
- ENSG00000136448
- RefSeq RNA
- NM_021079.5
- RefSeq protein
- NP_066565.1
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
N-myristoyltransferase 1
- Symbol
- NMT1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:44,957,992-45,109,016
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein NMT1 PDB 1rxt.png
Show 8 more facts
- HomoloGene ID
- 69027
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4836
- genomic end
- 43186384
- genomic start
- 44957992
- chromosome
- human chromosome 17
- cytogenetic location
- 17q21.31
- expressed in
- granulocyte
Sources (4)
via Wikidata · CC0