NMBR
Sign in to saveAlso known as BB1, NMB-R, neuromedin B receptor, BB1R, BRS1
protein-coding gene in the species Homo sapiens
Gene data
NMBR- Name
- neuromedin B receptor
- Type
- protein-coding
- Aliases
- BB1, BB1R, BRS1, NMB-R
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016].
via MyGene.info
Gene · Ensembl
neuromedin B receptor
- Symbol
- NMBR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:142,058,330-142,147,122
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/4829
- HomoloGene ID
- 20560
- genomic end
- 142147122
- genomic start
- 142379467
- cytogenetic location
- 6q24.1
Sources (3)
via Wikidata · CC0