NMBR
Sign in to saveAlso known as BB1, NMB-R, neuromedin B receptor, BB1R, BRS1
protein-coding gene in the species Homo sapiens
In the Vinony graph
Vinony's link graph records 488 inbound references to NMBR, and connects out to PubMed, Ensembl genome database project and cell surface receptor.
It is catalogued under topics including Genes on human chromosome 6 and G protein-coupled receptors.
Vinony links it to 5 Wikipedia language editions.
Gene data
NMBR- Name
- neuromedin B receptor
- Type
- protein-coding
- Position
- 142,058,330–142,147,122 (−)
- Aliases
- BB1, BB1R, BRS1, NMB-R
- Ensembl
- ENSG00000135577
- RefSeq RNA
- NM_001324307.2, NM_001324308.2, NM_002511.4
- RefSeq protein
- NP_001311236.1, NP_001311237.1, NP_002502.2
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
neuromedin B receptor
- Symbol
- NMBR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:142,058,330-142,147,122
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- exact match
- identifiers.org/ncbigene/4829
- HomoloGene ID
- 20560
- found in taxon
- Homo sapiens
- genomic end
- 142147122
- genomic start
- 142379467
- chromosome
- human chromosome 6
- cytogenetic location
- 6q24.1
- expressed in
- nucleus accumbens
Sources (3)
via Wikidata · CC0