OPRD1
Sign in to saveAlso known as OPRD, Δ-opioid receptor, opioid receptor delta 1, DOP, DOR1, DOR
protein-coding gene in the species Homo sapiens
Gene data
OPRD1- Name
- opioid receptor delta 1
- Type
- protein-coding
- Position
- 28,812,170–28,871,267 (+)
- Aliases
- DOP, DOR, DOR1, OPRD
- Ensembl
- ENSG00000116329
- RefSeq RNA
- NM_000911.4
- RefSeq protein
- NP_000902.3
Enables G protein-coupled enkephalin receptor activity. Involved in several processes, including G protein-coupled opioid receptor signaling pathway; cellular response to hypoxia; and positive regulation of peptidyl-serine phosphorylation. Is intrinsic component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
immune responseG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerphospholipase C-activating G protein-coupled receptor signaling pathwayphospholipase C-activating G protein-coupled receptor signaling pathwayneuropeptide signaling pathwaynegative regulation of gene expression
Molecular function
G protein-coupled receptor activityG protein-coupled opioid receptor activityG protein-coupled opioid receptor activityprotein bindingG protein-coupled peptide receptor activityreceptor serine/threonine kinase bindingG protein-coupled enkephalin receptor activityG protein-coupled enkephalin receptor activity
Pathways
cGMP-PKG signaling pathway - Homo sapiens (human)Sphingolipid signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Cytokine Signaling in Immune systemSignal TransductionImmune SystemSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Peptide ligand-binding receptorsGPCR downstream signalling
via MyGene.info
Gene · Ensembl
opioid receptor delta 1
- Symbol
- OPRD1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:28,812,089-28,871,267
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- 4n6h.png
Show 5 more facts
- HomoloGene ID
- 20252
- exact match
- identifiers.org/ncbigene/4985
- cytogenetic location
- 1p35.3
- genomic end
- 29190208
- genomic start
- 28812170
via Wikidata · CC0
Connections
Q180686
Entity
G protein-coupled recepteishon
Entity
(+)-catechin
Entity
Ensembl genome database project
Entity
butorphanol
Entity
Wikidata
Entity
chromosome
Entity
opium
Entity
digital object identifier
Entity
heroin
Entity
Papaver somniferum
Entity
morphine
Entity
pituitary gland
Entity
hypothalamus
Entity
(RS)-ketamine
Entity
pheromone
Entity
codeine
Entity
phenylalanine
Entity
bibcode
Entity
antidepressant
Entity