PALB2
Sign in to saveAlso known as FANCN, PNCA3, partner and localizer of BRCA2
Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene.
In the Vinony graph
Vinony's link graph records 81 inbound references to PALB2, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under topics including Genes on human chromosome 16 and Human proteins.
Vinony links it to 7 Wikipedia language editions.
Gene data
PALB2- Name
- partner and localizer of BRCA2
- Type
- protein-coding
- Position
- 23,603,158–23,641,342 (−)
- Aliases
- BROVCA5, FANCN, PNCA3
- Ensembl
- ENSG00000083093
- RefSeq RNA
- NM_001407296.1, NM_001407297.1, NM_001407298.1, NM_001407299.1, NM_001407300.1
- RefSeq protein
- NP_001394225.1, NP_001394226.1, NP_001394227.1, NP_001394228.1, NP_001394229.1
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
partner and localizer of BRCA2
- Symbol
- PALB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:23,603,158-23,641,342
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- PALB2 BRCA2.png
Show 8 more facts
- HomoloGene ID
- 11652
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79728
- genomic end
- 23652631
- genomic start
- 23614488
- chromosome
- human chromosome 16
- cytogenetic location
- 16p12.2
- genetic association
- urogenital neoplasm
Sources (7)
via Wikidata · CC0
~4 min read
Encyclopedic overview
7 sectionsContents
- Function
- Clinical significance
- Meiosis
- See also
- References
- Further reading
- External links
Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene.
== Function ==
Excerpted from Wikipedia’s “PALB2” article, available under the CC BY-SA 4.0 licence.