Structure via PubChem · Public domain (PubChem)
پارامتازون
Sign in to saveAlso known as Dillar, Paramethasone
Paramethasone is a fluorinated glucocorticoid with anti-inflammatory and immunosuppressant properties.
Chemical data
- Formula
- C22H29FO5
- Molecular weight
- 392.5 g/mol
- IUPAC name
- (6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
- SMILES
- C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)C)F
- InChIKey
- MKPDWECBUAZOHP-AFYJWTTESA-N
- XLogP
- 2
- Polar surface area
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
246 papers- Effect of paramethasone acetate on ovarian steroids and gonadotropins. I. Normal menstrual cycle.The Journal of clinical endocrinology and metabolism · 1975
- [Paramethasone in cardiology].Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille · 1963
- Effect of paramethasone acetate upon estrogen action.Fertility and sterility · 1982
- [Hiccups crisis following paramethasone intraarticular injection].Medicina clinica · 2005
- Clinical assessment of a new corticosteroid: paramethasone acetate.The Practitioner · 1963
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 392.2
- Has use
- medication
Show 6 more facts
- chemical formula
- C₂₂H₂₉FO₅
- canonical SMILES
- CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1(C(=O)CO)O)C)O)C)F
- isomeric SMILES
- C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)C)F
- subject has role
- glucocorticoid
- different from
- paramethadione
- defined daily dose
- 4
via Wikidata · CC0