PARP3
Sign in to saveAlso known as ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3, poly(ADP-ribose) polymerase family member 3
Poly [ADP-ribose] polymerase 3 is an enzyme that in humans is encoded by the PARP3 gene.
In the Vinony graph
Vinony's link graph records 3 inbound references to PARP3, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 3.
Vinony links it to 6 Wikipedia language editions.
Gene data
PARP3- Name
- poly(ADP-ribose) polymerase family member 3
- Type
- protein-coding
- Position
- 51,942,252–51,949,371 (+)
- Aliases
- ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3
- Ensembl
- ENSG00000041880
- RefSeq RNA
- NM_001003931.4, NM_001003935.2, NM_001370239.1, NM_001370240.1, NM_005485.6
- RefSeq protein
- NP_001003931.4, NP_001357168.1, NP_001357169.1, NP_005476.4, XP_047303043.1
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
poly(ADP-ribose) polymerase family member 3
- Symbol
- PARP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:51,942,252-51,949,371
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PARP3 PDB 2pa9.png
Show 8 more facts
- HomoloGene ID
- 4005
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10039
- genomic end
- 51982883
- genomic start
- 51976361
- chromosome
- human chromosome 3
- cytogenetic location
- 3p21.2
- Commons category
- PARP3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Poly [ADP-ribose] polymerase 3 is an enzyme that in humans is encoded by the PARP3 gene.
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Excerpted from Wikipedia’s “PARP3” article, available under the CC BY-SA 4.0 licence.