PDC

Also known as MEKA, PHD, PhLOP, PhLP, phosducin

Phosducin, also known as PDC, is a human protein and gene. It belongs to the phosducin family of proteins.

Gene data

PDC

Name: phosducin
Type: protein-coding
Aliases: MEKA, PHD, PhLOP, PhLP

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

phosducin

Symbol: PDC
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:186,443,566-186,461,114
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein PDC PDB 2trc.png

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HomoloGene ID: 1950
exact match: identifiers.org/ncbigene/5132
genomic end: 186461114
genomic start: 186412698
cytogenetic location: 1q31.1

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Phosducin, also known as PDC, is a human protein and gene. It belongs to the phosducin family of proteins.

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. By associating with these subunits only, the transducin alpha subunit will remain active for longer. This will increase the amount of time of visual excitation.