PDCD7

Also known as ES18, HES18, programmed cell death 7, 59K

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene.

In the Vinony graph

Within Vinony's link graph, PDCD7 is referenced by 2 other articles, and connects out to PubMed, human chromosome 15 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 15.

Its subject is documented across 7 Wikipedia language editions.

Gene data

PDCD7

Name: programmed cell death 7
Type: protein-coding
Position: 65,117,379–65,133,836 (−)
Aliases: 59K, ES18, HES18
Ensembl: ENSG00000090470
RefSeq RNA: NM_005707.2
RefSeq protein: NP_005698.1

This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010].

Gene Ontology

Biological process

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)mRNA splicing, via spliceosome RNA splicing response to glucocorticoid

Cellular component

nucleus nucleoplasm spliceosomal complex U12-type spliceosomal complex U12-type spliceosomal complex U12-type spliceosomal complex U11/U12 snRNP U12-type precatalytic spliceosome

Pathways

mRNA Splicing - Minor Pathway mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA Metabolism of RNA

via MyGene.info

Gene · Ensembl

programmed cell death 7

Symbol: PDCD7
Biotype: Protein coding
Organism: Homo sapiens
Location: 15:65,117,379-65,133,836
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

exact match: identifiers.org/ncbigene/10081
HomoloGene ID: 4170
found in taxon: Homo sapiens
genomic end: 65133808
genomic start: 65409717
chromosome: human chromosome 15
cytogenetic location: 15q22.31
expressed in: medulla oblongata

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

3 sections

Contents

References
Further reading
External links

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene.

This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.

Excerpted from Wikipedia’s “PDCD7” article, available under the CC BY-SA 4.0 licence.