PDCD7

Also known as ES18, HES18, programmed cell death 7, 59K

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene.

Gene data

PDCD7

Name: programmed cell death 7
Type: protein-coding
Position: 65,117,379–65,133,808 (−)
Aliases: 59K, ES18, HES18
Ensembl: ENSG00000090470
RefSeq RNA: NM_005707.2
RefSeq protein: NP_005698.1

This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010].

Gene Ontology

Biological process

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)mRNA splicing, via spliceosome RNA splicing response to glucocorticoid

Cellular component

nucleus nucleoplasm U12-type spliceosomal complex U12-type spliceosomal complex

Pathways

mRNA Splicing - Minor Pathway mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA Metabolism of RNA

via MyGene.info

Gene · Ensembl

programmed cell death 7

Symbol: PDCD7
Biotype: Protein coding
Organism: Homo sapiens
Location: 15:65,117,379-65,133,836
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

exact match: identifiers.org/ncbigene/10081
HomoloGene ID: 4170
genomic end: 65133808
genomic start: 65409717
cytogenetic location: 15q22.31

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Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene.

This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.