CDCA7
Sign in to saveAlso known as JPO1, ICF3, cell division cycle associated 7
Cell division cycle-associated protein 7 is a protein that in humans is encoded by the CDCA7 gene.
Gene data
CDCA7- Name
- cell division cycle associated 7
- Type
- protein-coding
- Position
- 173,354,820–173,368,997 (+)
- Aliases
- ICF3, JPO1
- Ensembl
- ENSG00000144354
- RefSeq RNA
- NM_031942.5, NM_145810.3, XM_047445957.1, XM_054344112.1
- RefSeq protein
- NP_114148.3, NP_665809.1, XP_047301913.1, XP_054200087.1
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
cell division cycle associated 7
- Symbol
- CDCA7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:173,354,818-173,368,997
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 49970
- exact match
- identifiers.org/ncbigene/83879
- genomic end
- 174233725
- genomic start
- 174219548
- cytogenetic location
- 2q31.1
via Wikidata · CC0
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Article
3 sectionsContents
- References
- External links
- Further reading
Cell division cycle-associated protein 7 is a protein that in humans is encoded by the CDCA7 gene.
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.