PERP
Sign in to saveAlso known as KCP1, KRTCAP1, PIGPC1, THW, dJ496H19.1, PERP, TP53 apoptosis effector, p53 apoptosis effector related to PMP22, EKVP7
p53 apoptosis effector related to PMP-22 is a plasma membrane protein that, in humans, is encoded by the PERP gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to PERP, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Vinony links it to 6 Wikipedia language editions.
Gene data
PERP- Name
- p53 apoptosis effector related to PMP22
- Type
- protein-coding
- Position
- 138,015,003–138,107,848 (−)
- Aliases
- EKVP7, KCP1, KRTCAP1, OLMS2, PIGPC1, THW, dJ496H19.1
- Ensembl
- ENSG00000112378
- RefSeq RNA
- NM_022121.5
- RefSeq protein
- NP_071404.2
Involved in activation of cysteine-type endopeptidase activity. Predicted to be located in plasma membrane. Predicted to be active in cell-cell junction. Implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
p53 apoptosis effector related to PMP22
- Symbol
- PERP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:138,015,003-138,107,848
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 11098
- genetic association
- bulimia nervosa
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/64065
- genomic end
- 138107419
- genomic start
- 138409642
- chromosome
- human chromosome 6
- cytogenetic location
- 6q23.3
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
p53 apoptosis effector related to PMP-22 is a plasma membrane protein that, in humans, is encoded by the PERP gene.
PERP is a direct transcriptional target of p53, but its transcription can also be regulated by other transcription factors.
Excerpted from Wikipedia’s “PERP” article, available under the CC BY-SA 4.0 licence.