Structure via PubChem · Public domain (PubChem)
pirbuterol
Sign in to saveAlso known as CP-24314-1, CP-24314-14, CP-2431414, Maxair®, Pirbuterolum, (+/-)-pirbuterol
Pirbuterol (trade name Maxair) is a short-acting β2 adrenoreceptor agonist with bronchodilating action used in the treatment of asthma, available (as pirbuterol acetate) as a breath-activated metered-dose inhaler.
Chemical data
- Formula
- C12H20N2O3
- Molecular weight
- 240.3 g/mol
- IUPAC name
- 6-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)pyridin-3-ol
- SMILES
- CC(C)(C)NCC(C1=NC(=C(C=C1)O)CO)O
- InChIKey
- VQDBNKDJNJQRDG-UHFFFAOYSA-N
- XLogP
- -0.1
- Polar surface area
- 85.6 Ų
- H-bond donors
- 4
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1986
- Admin. routes
- topical
- Indications
- Airway obstruction
via ChEMBL · EBI
Research
151 papers- Pirbuterol.2006
- Pirbuterol hydrochloride: evaluation of beta adrenergic agonist activity in reversible obstructive pulmonary disease and congestive heart failure.Pharmacotherapy · 1984
- Pirbuterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible bronchospastic disease.Drugs · 1985
- Pirbuterol.Lancet (London, England) · 1984
- Intravenous pirbuterol.Clinical pharmacology and therapeutics · 1982
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 240.147393
- Has use
- medication
Show 9 more facts
- chemical formula
- C₁₂H₂₀N₂O₃
- World Health Organisation international non-proprietary name
- pirbuterol
- medical condition treated
- asthma
- canonical SMILES
- CC(C)(C)NCC(C1=NC(=C(C=C1)O)CO)O
- defined daily dose
- 1.2
- subject has role
- cardiotonic
- Commons category
- Pirbuterol
- found in taxon
- Caenorhabditis elegans
- physically interacts with
- adrenoceptor beta 2
via Wikidata · CC0
~1 min read
Encyclopedic overview
6 sectionsContents
- Medical use
- Mode of action
- Pharmacokinetics
- Adverse effects
- References
- External links
Pirbuterol (trade name Maxair) is a short-acting β2 adrenoreceptor agonist with bronchodilating action used in the treatment of asthma, available (as pirbuterol acetate) as a breath-activated metered-dose inhaler.
It was patented in 1971 and came into medical use in 1983.
Excerpted from Wikipedia’s “pirbuterol” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0