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propiomazine

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Also known as CB-1678, WY-1359, 3-propionyl-10-dimethylaminoisopropylphenothiazine, 10-(2-dimethylaminopropyl)-2-propionylphenothiazine, 2-propionyl-10-[2-(dimethylamino)propyl]phenothiazine

Propiomazine, sold under the brand name Propavan among others, is an antihistamine which is used to treat insomnia and to produce sedation and relieve anxiety before or during surgery or other procedures and in combination with analgesics as well as during labor. Propiomazine is a phenothiazine, but is not used therapeutically as a neuroleptic because it does not block dopamine receptors well.

Wikidata facts

Mass
340.160934
Show 5 more facts
chemical formula
C₂₀H₂₄N₂OS
defined daily dose
25.0
World Health Organisation international non-proprietary name
propiomazine
canonical SMILES
CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CC(C)N(C)C
Commons category
Propiomazine
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9 sections
Contents
  • Medical uses
  • Side effects
  • Pharmacology
  • Pharmacodynamics
  • Chemistry
  • Society and culture
  • Brand names
  • Availability
  • References

Propiomazine, sold under the brand name Propavan among others, is an antihistamine which is used to treat insomnia and to produce sedation and relieve anxiety before or during surgery or other procedures and in combination with analgesics as well as during labor. Propiomazine is a phenothiazine, but is not used therapeutically as a neuroleptic because it does not block dopamine receptors well.

==Medical uses== Propiomazine has been used in the treatment of insomnia.

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