PTGDR2

Also known as CD294, CRTH2, DL1R, DP2, GPR44, prostaglandin D2 receptor 2

protein-coding gene in the species Homo sapiens

Gene data

PTGDR2

Name: prostaglandin D2 receptor 2
Type: protein-coding
Position: 60,850,933–60,855,950 (−)
Aliases: CD294, CRTH2, DL1R, DP2, GPR44
Ensembl: ENSG00000183134
RefSeq RNA: NM_004778.3
RefSeq protein: NP_004769.2

This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011].