Thromboxane A2 receptor

Protein · UniProt

Thromboxane A2 receptor

Gene

TBXA2R

Organism

Homo sapiens (Human)

Length

343 aa

Molecular mass

37,431 Da

Evidence

1: Evidence at protein level

Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C

• PHASE4RECRUITING
  Thromboxane Function in Women With EndometriosisPenn State University · NCT05962034
• PHASE2ACTIVE_NOT_RECRUITING
  Ifetroban in Treating Patients With Malignant Solid Tumors at High Risk of Metastatic RecurrenceVanderbilt-Ingram Cancer Center · NCT03694249

via ClinicalTrials.gov