iloprost

Also known as ZK-00036374, (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]hexahydro-2(1H)-pentalenylidene]pentanoic acid, (RS)-iloprost

Iloprost, sold under the brand name Ventavis among others, is a medication used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon, frostbite, and other conditions in which the blood vessels are constricted and blood cannot flow to the tissues. Iloprost is a prostacyclin mimetic.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 443868674
Drug.image: Iloprost 2D structure.svg
Drug.image_class: skin-invert-image
Drug.width: 250
Drug.image2: Iloprost.png
Drug.image_class2: bg-transparent
Drug.tradename: Ventavis, Ilomedine, Aurlumyn
Drug.MedlinePlus: a612032
Drug.DailyMedID: Iloprost
Drug.routes_of_administration: Inhalation, intravenous
Drug.ATC_prefix: B01
Drug.ATC_suffix: AC11
Drug.legal_US: Rx-only
Drug.legal_EU: Rx-only
Drug.legal_status: Rx-only
Drug.bioavailability: Not determined

via Wikipedia infobox

Wikidata facts

Mass: 360.23006
Has use: medication

Show 8 more facts

World Health Organisation international non-proprietary name: iloprost
chemical formula: C₂₂H₃₂O₄
canonical SMILES: CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
isomeric SMILES: CC#CCC(C)[C@@H](/C=C/[C@H]1[C@@H](C[C@H]2[C@@H]1C/C(=C/CCCC(=O)O)/C2)O)O
subject has role: platelet aggregation inhibitors
Commons category: Iloprost
physically interacts with: Prostaglandin I2 receptor
significant drug interaction: apixaban

Sources (5)

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Encyclopedic overview

6 sections

Contents

Medical uses
Pharmacology
Contraindications
Side effects
References
Further reading

{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 443868674 | image = Iloprost 2D structure.svg | image_class = skin-invert-image | width = 250 | alt = | image2 = Iloprost.png | image_class2 = bg-transparent | pronounce = | tradename = Ventavis, Ilomedine, Aurlumyn | Drugs.com = | MedlinePlus = a612032 | DailyMedID = Iloprost | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = Inhalation, intravenous | class = | ATC_prefix = B01 | ATC_suffix = AC11 | ATC_supplemental = | legal_US = Rx-only | legal_US_comment = | legal_EU = Rx-only | legal_EU_comment = | legal_status = Rx-only

Excerpted from Wikipedia’s “iloprost” article, available under the CC BY-SA 4.0 licence.

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