Ranimustine

Ranimustine (INN, marketed under the tradename Cymerin; also known as MCNU) is a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera.

In the Vinony graph

Vinony's link graph records 271 inbound references to Ranimustine, and connects out to tiazofurin, United States and Japan.

It is catalogued under topics including Alkylating antineoplastic agents, Chemical pages without DrugBank identifier and Chloroethyl compounds.

Vinony links it to 7 Wikipedia language editions.

Chemical data

Formula: C10H18ClN3O7
Molecular weight: 327.72 g/mol
IUPAC name: 1-(2-chloroethyl)-1-nitroso-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]methyl]urea
SMILES: CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CNC(=O)N(CCCl)N=O)O)O)O
InChIKey: AHHFEZNOXOZZQA-ZEBDFXRSSA-N
XLogP: -1.7
Polar surface area: 141 Å²
H-bond donors: 4
H-bond acceptors: 8
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule
Indications: neoplasm, adult T-cell leukemia/lymphoma

via ChEMBL · EBI

Research

233 papers

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 327.083
Has use: medication

Show 5 more facts

chemical formula: C₁₀H₁₈ClN₃O₇
isomeric SMILES: CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CNC(=O)N(CCCl)N=O)O)O)O
canonical SMILES: COC1C(C(C(C(O1)CNC(=O)N(CCCl)N=O)O)O)O
subject has role: antineoplastic
Commons category: Ranimustine

Sources (2)

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