Structure via PubChem · Public domain (PubChem)
رانیموستین
Sign in to saveAlso known as Ranimustine
Ranimustine (INN, marketed under the tradename Cymerin; also known as MCNU) is a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera.
In the Vinony graph
Within Vinony's link graph, رانیموستین is referenced by 271 other articles, and connects out to tiazofurin, United States and Japan.
Vinony files it under Alkylating antineoplastic agents, Chemical pages without DrugBank identifier and Chloroethyl compounds.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C10H18ClN3O7
- Molecular weight
- 327.72 g/mol
- IUPAC name
- 1-(2-chloroethyl)-1-nitroso-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]methyl]urea
- SMILES
- CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CNC(=O)N(CCCl)N=O)O)O)O
- InChIKey
- AHHFEZNOXOZZQA-ZEBDFXRSSA-N
- XLogP
- -1.7
- Polar surface area
- 141 Ų
- H-bond donors
- 4
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- neoplasm, adult T-cell leukemia/lymphoma
via ChEMBL · EBI
Research
233 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 327.083
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₀H₁₈ClN₃O₇
- isomeric SMILES
- CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CNC(=O)N(CCCl)N=O)O)O)O
- canonical SMILES
- COC1C(C(C(C(O1)CNC(=O)N(CCCl)N=O)O)O)O
- subject has role
- antineoplastic
- Commons category
- Ranimustine
Sources (2)
via Wikidata · CC0
Connections
tiazofurin
Entity
United States
Country
Japan
Country
medication
Entity
digital object identifier
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leukemia
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chemical formula
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chemotherapy
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amine
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molar mass
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PubMed
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DNA replication
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hydrazine
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cell cycle
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DL-asparagine
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CAS Registry Number
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United States Food and Drug Administration
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PubChem
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microtubule
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Anatomical Therapeutic Chemical Classification System
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