RGS6

Name

regulator of G protein signaling 6

Type

protein-coding

Position

71,931,979–72,566,530 (+)

Aliases

GAP, HA117, S914

Ensembl

ENSG00000182732

RefSeq RNA

NM_001204416.3, NM_001204417.3, NM_001204418.3, NM_001204419.3, NM_001204420.3

RefSeq protein

NP_001191345.1, NP_001191346.1, NP_001191347.1, NP_001191348.1, NP_001191349.1

This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011].

via MyGene.info

Gene · Ensembl

regulator of G protein signaling 6

Symbol

RGS6

Biotype

Protein coding

Organism

Homo sapiens

Location

14:71,931,979-72,566,530

Strand

Forward (+)

Assembly

GRCh38