rolitetracycline
Sign in to saveAlso known as Syntetrin, SO-15659, Rolitetraciclina, N-(1-Pyrrolidinylmethyl)-tetracycline, Synterin, N-(Pyrrolidinomethyl)tetracycline, Reverin, Pyrrolidino-methyl-tetracycline
Rolitetracycline is a tetracycline antibiotic. Tetracycline is N-Mannich base prodrug that is prepared from tetracycline by condensation with pyrrolidine and formaldehyde to produce rolitetracycline. Rolitetracycline is used as an antibacterial drug, a protein synthesis inhibitor, an antiprotozoal drug and a prodrug.
Research
404 papers- Tetracyclines.2012
- Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines.The Journal of antimicrobial chemotherapy · 2006
- The site of the neuromuscular block produced by polymyxin B and rolitetracycline.Canadian journal of physiology and pharmacology · 1976
- Binding and displacement study of gentamicin, 5-fluorouracil, oxytetracycline and rolitetracycline with (BSA: Drug2) complex using spectroscopic and calorimetric techniques: Biophysical approach.International journal of biological macromolecules · 2024
- Combination of bacteriostatic and bactericidal drugs: lack of significant in vitro antagonism between penicillin, cephalothin, and rolitetracycline.Antimicrobial agents and chemotherapy · 1976
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Encyclopedic overview
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- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464383386 | IUPAC_name = (2Z,4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-6,10,11,12a-tetrahydroxy-2-{hydroxy[(pyrrolidin-1-ylmethyl)amino]methylene}-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione | image = Rolitetracycline.svg | image_class = skin-invert-image | alt = Skeletal formula of rolitetracycline | width = 240 | image2 = Rolitetracycline 3D spacefill.png | image_class2 = bg-transparent | alt2 = Space-filling model of the rolitetracycline molecule | width2 = 260
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
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