Also known as AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 1
SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene.
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].
via MyGene.info
SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene.
== Interactions ==
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).