SERPINA4

Also known as KAL, KLST, KST, PI-4, PI4, kallistatin, serpin family A member 4

Kallistatin is a protein that in humans is encoded by the SERPINA4 gene.

Gene data

SERPINA4

Name: serpin family A member 4
Type: protein-coding
Position: 94,561,390–94,570,482 (+)
Aliases: KAL, KLST, KST, PI-4, PI4, kallistatin
Ensembl: ENSG00000100665
RefSeq RNA: NM_001289032.2, NM_001289033.2, NM_006215.4
RefSeq protein: NP_001275961.1, NP_001275962.1, NP_006206.2

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Located in extracellular exosome. Biomarker of diabetic retinopathy. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Molecular function

serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity

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See also
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Kallistatin is a protein that in humans is encoded by the SERPINA4 gene.

Kallistatin consists of three folded ß segments and eight helical structures and contains two functional domains, an active site and a heparin-binding site.