SERPINA4
Sign in to saveAlso known as KAL, KLST, KST, PI-4, PI4, kallistatin, serpin family A member 4
Kallistatin is a protein that in humans is encoded by the SERPINA4 gene.
Gene data
SERPINA4- Name
- serpin family A member 4
- Type
- protein-coding
- Position
- 94,561,390–94,570,995 (+)
- Aliases
- KAL, KLST, KST, PI-4, PI4, kallistatin
- Ensembl
- ENSG00000100665
- RefSeq RNA
- NM_001289032.2, NM_001289033.2, NM_006215.4
- RefSeq protein
- NP_001275961.1, NP_001275962.1, NP_006206.2
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Located in extracellular exosome. Biomarker of diabetic retinopathy. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
serpin family A member 4
- Symbol
- SERPINA4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:94,561,390-94,570,995
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Kallistatin is a protein that in humans is encoded by the SERPINA4 gene.
Kallistatin consists of three folded ß segments and eight helical structures and contains two functional domains, an active site and a heparin-binding site.
Excerpted from Wikipedia’s “SERPINA4” article, available under the CC BY-SA 4.0 licence.