SMARCA2
Sign in to saveAlso known as BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p
Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.
Gene data
SMARCA2- Name
- SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
- Type
- protein-coding
- Aliases
- BAF190, BIS, BRM, NCBRS, SAMRCA2, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014].
via MyGene.info
Gene · Ensembl
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
- Symbol
- SMARCA2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:1,980,290-2,193,624
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein SMARCA2 PDB 2dat.png
Show 5 more facts
- HomoloGene ID
- 2308
- exact match
- identifiers.org/ncbigene/6595
- genomic end
- 2193624
- genomic start
- 2015342
- cytogenetic location
- 9p24.3
Sources (8)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.
== Function ==