Also known as SLUG, SLUGH1, SNAIL2, WS2D, snail family transcriptional repressor 2, SLUGH
Zinc finger protein SNAI2 (also called SLUG) is a transcription factor that in humans is encoded by the SNAI2 gene. It promotes epithelial to mesenchymal transition, differentiation (e.g. in gastrulation), and migration of cells.
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008].
via MyGene.info
~4 min read
Zinc finger protein SNAI2 (also called SLUG) is a transcription factor that in humans is encoded by the SNAI2 gene. It promotes epithelial to mesenchymal transition, differentiation (e.g. in gastrulation), and migration of cells.
== Function ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).