SSTR5
Sign in to saveAlso known as SS-5-R, Somatostatin receptor 5
protein-coding gene in the species Homo sapiens
Gene data
SSTR5- Name
- somatostatin receptor 5
- Type
- protein-coding
- Position
- 1,063,867–1,081,467 (+)
- Aliases
- SS-5-R, SST5
- Ensembl
- ENSG00000162009
- RefSeq RNA
- NM_001053.4, NM_001172560.3, NM_001172572.1, NM_001172573.1
- RefSeq protein
- NP_001044.1, NP_001166031.1
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
somatostatin receptor 5
- Symbol
- SSTR5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:1,063,867-1,081,470
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 20287
- exact match
- identifiers.org/ncbigene/6755
- genomic end
- 1081454
- genomic start
- 1072747
- cytogenetic location
- 16p13.3
Sources (3)
via Wikidata · CC0